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smeriglio holdings inc

smeriglio holdings incsmeriglio holdings incsmeriglio holdings inc

Rx Consulting & Capital

Rx Consulting & CapitalRx Consulting & Capital

Company Overview from our Founder

smeriglio, pharmaceutical marketing, drug licensing, frank smeriglio,

Frank Smeriglio, BSc (hons), BEd, MBA

After holding senior positions with a number of leading medical marketing and CME agencies, Frank founded smeriglio holdings inc in 2010 with the intent of building a dual division company exclusively focused on specialty drugs and rare diseases. Today, we are pleased to see our vision realized through our Rx Consulting and Capital divisions.


The Rx Consulting division is where we spend most of our time and energy. This division was inspired by the need to bring a new agency model to market, one that is focused only on a few clients, a few brands, and in therapeutic areas we know well. With this model now operational for many years, we are able to remain hyper-focused on the client and their brand(s) and ultimately, their success.


The Capital division of our business houses, in part, our investments into privately controlled healthcare companies, such as iNVARON Pharmaceuticals Inc., The Canadian Fertility Institute Inc., and neuroceutika inc., to name a few. We also manage a biotech portfolio within the Capital division which is comprised of a healthy balance of large and speculative small caps equities.


We continuously seek out additional niche brands to bring to Canada via Licensing /Distribution Agreement either through one of the aforementioned companies, through a de novo corporate creation, or by finding International Licensor's Canadian Partners.

Business Philosophy & Approach

Rx Consulting Division

Our general business philosophy can be summarized and characterized by the following key points:  

  • Niche and specialty drugs - we focus on drugs that are characterized by high transaction value (or prescription value), but lower transaction volumes which have included rare diseases like SCD, thalassemia, and biologic disease modifying therapies, such as in multiple sclerosis, psoriasis, rheumatoid arthritis, and the like.
  • Understand the science and behaviours - we are an evidence-based marketing service provider, reviewing and understanding the clinical evidence supporting the brand, it's key messages, competitive set and how, if at all, these factors may influence prescribers.
  •  Fewer clients and brands - we have structured our business so as to partner with clients over a multi-year Term from pre-launch through to launch and are able to accomplish this by being small, focused, and customer/brand-centric. This approach results in 1) Diminished need for new business activity, 2) Focus only on certain therapeutic areas and clients at any given time and 3) Fewer brands in the portfolio means we can keep current, have bandwidth
  •  Migrate value to the client - with fewer clients and brands in the portfolio mean we can develop proactive proposals and concepts, all coupled with a lower overhead model 
  • It all starts with our primary offering - turnkey Consultant Meetings, also known as advisory boards, including Investigator Meetings. We help clients in pre-launch through to the first few years of launch / commercial availability. Our offering can include content, logistics, and compliance management with your important KOL customers and influencers.

Capital Division - Licensing & Business Development

We have provided equity financing to several healthcare companies, including a privately held Canadian pharmaceutical company with a focus on medical devices for reproductive medicine and a healthcare services company. We are in the process of finalizing our exits from these companies and are looking for our next investment. 


We are presently seeking brands for licensing into Canada directly - these brands would have some of the following characteristics: 

  1. Rare disease or niche brand
  2. Want to expand the markets your are selling into via Licensing / Distribution Agreement 
  3. Want a local to manage regulatory, become the Market Authorization Holder 

Looking to license into Canada?

Select Therapeutic Areas of Specialty

Neurology & CNS

Hematology / Immunology

Hematology / Immunology

multiple sclerosis, Parkinson's disease, Neurodegenerative, psychiatry, antidepressant, ADHD

  1. Multiple sclerosis disease modifiers
  2. Parkinson's disease, epilepsy  
  3. Anti-depressants, ADHD

Hematology / Immunology

Hematology / Immunology

Hematology / Immunology

Autoimmune disorders (MS, SLE) Extensive biologics experience, immunosuppressant, immunomodulators

  1. Thalasssemia, Sickle Cell, MDS
  2. Autoimmune disorders (MS, SLE)
  3. Immunosuppressant & immunomodulating biologics

Dermatology

Hematology / Immunology

Muskuloskeletal

Biologics for psoriasis Acne, rosacea, atopic dermatitis, eczema

  1. Clinical dermatology focus 
  2. Biologics for psoriasis
  3. Acne, rosacea, atopic dermatitis

Muskuloskeletal

Muskuloskeletal

Muskuloskeletal

  1. Rheumatoid arthritis disease modifiers
  2. Visco-supplementation
  3. Osteoarthritis, NSAIDs

Cardiovascular

Muskuloskeletal

Cardiovascular

Anti-sense oligonucleotides for LDL-C PCSK9 & other non-statins Statins

  1. Anti-sense oligonucleotide technology
  2. PCSK9 & other non-statins
  3. Statins

Cannabis

Muskuloskeletal

Cardiovascular

  1. Medical cannabis only
  2. Prescriber (doctor & nurse) focus
  3. Evidence based approach, CME


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